![]() Thus, the clinical diagnosis of mild or major NCD is established mainly based on the person’s performance on different cognitive domains, and its functionality in everyday activities. However, it has also been described that cognitive decline observed in major NCD is significantly higher than that described for mild NCD, and it is also accompanied by an important deterioration of daily life activities. consider mild NCD as an intermediate stage of cognitive impairment that is often, but not always, a transitional phase from mild to major NCD. These results showed that the MoCA is a suitable tool to identify mild NCD and major NCD.Ĭlinical evidence indicates that approximately 35% of amnestic mild NCD cases evolve to major NCD after 2 years of onset. ![]() ![]() Conclusion: Overall diagnostic accuracy can be considered as outstanding (AUC ≥0.904) when discriminating HE from both mild NCD and major NCD. The cut-off between mild NCD and major NCD from HE participants was 19 points with 85.6% of sensitivity and 90.3% of specificity. The observed balance between sensitivity and specificity shows a good test performance either to confirm or discard a diagnosis. Results: The optimal cut-off score to discriminate mild NCD from HE participants was 20 points with a sensitivity of 82.8% and a specificity of 84.1%. ![]() Methods: This study included 226 participants from the north, center, and south of the country, classified into 3 groups: healthy elderly (HE n = 113), mild NCD ( n = 65), and major neurocognitive disorder (major NCD n = 48). In this context, the aim of this study was to update the normative values, and diagnostic efficiency statistics of the MoCA to detect mild NCD in the Chilean population. However, cut-off scores and accuracy indices should be established using representative samples of the population. Background: The Montreal Cognitive Assessment (MoCA) is a sensitive screening instrument for mild neurocognitive disorder (mild NCD). ![]()
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